Publications

Hemarina est une société de biotechnologie qui possède une forte activité de R&D. Nos équipes possèdent un savoir faire unique, basé sur une quinzaine d'années de recherche fondamentale. Les résultats de nos travaux de recherche font l’objet de nombreux articles scientifiques publiés dans des journaux de premier plan.

Technologie Hemarina

Le Pape, F., Richard, G., Porchet, E., Sourice, S., Dubrana, F., Férec, C., Polard, V., Pace, R., Weiss, P., Zal, F., Delépine, P., Leize, E.
Adhesion, proliferation and osteogenic differentiation of human MSCs cultured under perfusion with a marine oxygen carrier on an allogenic bone substitute.
Artificial Cells, Nanomedicine, and Biotechnology, 46(1):95-107. - 2018
https://www.ncbi.nlm.nih.gov/pubmed/28830269

Marchand, A., Crepin, N., Roulland, I., Semence, F., Domergue, V., Zal, F., Polard, V., Coquerel, A.
Application of HBOCs electrophoretic method to detect a new blood substitute derived from the giant extracellular hemoglobin of lugworm.
Drug Testing and Analysis, 9(11-12):1762-1767. - 2017
https://www.ncbi.nlm.nih.gov/pubmed/27787946

Polard, V., Alix, P.
Evaluation of a specific oxygen carrier (M101®) added to pig liver cold storage solutions to improve post-transplant graft function.
Presented at the XVI ISBS, held November 13-15, 2017 in Montréal, Canada. - 2017

Moon-Massat, P., Mullah, S.H., Abutarboush, R., Saha, B.K., Pappas, G., Haque, A., Auker, C., McCarron, R.M., Arnaud, F., Scultetus, A.
Cerebral Vasoactivity and Oxygenation with Oxygen Carrier M101 in Rats.
Journal of Neurotrauma, 34(19):2812-2822. - 2017
https://www.ncbi.nlm.nih.gov/pubmed/26161914

Teh, E. S., Zal, F., Polard, V., Menasché, P., Chambers, D.J.
HEMO2life® as a protective additive to Celsior solution for static storage of donor hearts prior to transplantation.
Artificial Cells, Nanomedicine, and Biotechnology, 45(4):717-722. - 2017
https://www.ncbi.nlm.nih.gov/pubmed/28079401

Le Pape, F., Cosnuau-Kemmat, L., Richard, G., Dubrana, F., Férec, C., Zal, F., Leize, E., Delépine, P.
HEMOXCell, a New Oxygen Carrier Usable as an Additive for Mesenchymal Stem Cell Culture in Platelet Lysate-Supplemented Media.
Artificial Organs, 41(4):359-371. - 2017
https://www.ncbi.nlm.nih.gov/pubmed/28326561

Rodriguez-Brotons, A., Bietiger, W., Peronet, C., Langlois, A., Magisson, J., Mura, C., Sookhareea, C., Polard, V., Jeandidier, N., Zal, F., Pinget, M., Sigrist, S., Maillard, E.
Comparison of Perfluorodecalin and HEMOXCell as Oxygen Carriers for Islet Oxygenation in an In Vitro Model of Encapsulation.
Tissue Engineering Part A, 22(23-24):1327-1336 - 2016
https://www.ncbi.nlm.nih.gov/pubmed/27796164

Le Pape, F., Bossard, M., Dutheil, D., Rousselot, M., Polard, V., Férec, C., Leize, E., Delépine, P., Zal, F.
Advancement in recombinant protein production using a marine oxygen carrier to enhance oxygen transfer in a CHO-S cell line.
Artificial Cells, Nanomedicine, and Biotechnology, 43(3):186-195. - 2015
https://www.ncbi.nlm.nih.gov/pubmed/25961365

Le Gall, T., Polard, V., Rousselot, M., Lotte, A., Raouane, M., Lehn, P., Opolon, P., Leize, E., Deutsch, E., Zal, F., Montier, T.
In vivo biodistribution and oxygenation potential of a new generation of oxygen carrier
Journal of Biotechnology, 187:1-9. - 2014
https://pubmed.ncbi.nlm.nih.gov/25034433/

Mallet, V., Dutheil, D., Polard, V., Rousselot, M., Leize, E., Hauet, T., Goujon, J.-M., Zal, F.
Dose-Ranging study of the performance of the natural oxygen transporter HEMO2life® in organ preservation.
Artificials Organs, 38(8):691-701. - 2014
https://www.ncbi.nlm.nih.gov/pubmed/24749976