publication

Hemarina est une société de biotechnologie qui possède une forte activité de R&D. Nos équipes possèdent un savoir faire unique, basé sur une quinzaine d'années de recherche fondamentale. Les résultats de nos travaux de recherche font l’objet de nombreux articles scientifiques publiés dans des journaux de premier plan. 

HEMO2life®

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Le Meur, Y., Morelon, E., Essig, M., Thierry, A., Büchler, M., Drouin, S., Deruelle, C., Badet, L., Pesteil, F., Delpech, P-O., Boutin, J-M., Renard, F., Barrou, B. First-in-human use of a marine oxygen carrier for organ preservation: a safety and proof-of-principle study (submitted).

pancreas

Lemaire, F., Sigrist, S., Delpy, E., Cherfan, J., Peronet, C., Zal, F., Bouzakri, K., Pinget, M., Maillard, E. Beneficial effects of the novel marine oxygen carrier M101 during cold preservation of rat and human pancreas.
Journal of Cellular and Molecular Medicine. 2019                
https://onlinelibrary.wiley.com/doi/full/10.1111/jcmm.14666

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Kasil, A., Giraud, S., Couturier, P., Amiri, A., Danion, J., Donatini, G., Matillon, X., Hauet, T., Badet, L. 
Individual and combined impact of oxygen and oxygen transporter supplementation during kidney machine preservation in a porcine preclinical kidney transplantation model. International Journal of Molecular Sciences, 20(8). 2019
https://www.ncbi.nlm.nih.gov/pubmed/31018558

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Thuillier, R., Delpy, E., Matillon, X., Kaminski J., Kasil, A., Soussi, D., Danion, J., Sauvageon, Y., Rod, X., Donatini, G., Barrou, B., Badet, L., Zal, F., Hauet, T. Preventing acute kidney injury during transplantation: the application of novel oxygen carriers. Expert Opinion on Investigational Drugs, 28(7):643-657. 2019
https://www.ncbi.nlm.nih.gov/pubmed/31165652

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Kaminski, J., Hannaert, P., Kasil,A., Thuillier, R., Leize, E., Delpy, E., Steichen, C., Goujon, J.-M., Zal, F.,  Hauet, T. Efficacy of the natural oxygen transporter HEMO2life® in cold preservation in a preclinical porcine model of donation after cardiac death. Transplant International, official journal of the European Society for Organ Transplantation. 2019
https://www.ncbi.nlm.nih.gov/pubmed/30924562

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Ali, A., Watanabe, Y., Galasso, M., Stansfield, W., Watanabe, T., Ramandan, K., Chen, M., Ribeiro, R.P., Gokhale, H., Gazzalle, A., Waddell, T., Liu, M., Keshavjee, S., Cypel, M. Two-Day Lung Preservation Followed by Lung Transplantation in a Large Animal Model Using Novel Extracellular Oxygen Carrier. The Journal of Heart and Lung Transplantation, 37(4): S123-S124. 2018 
https://www.jhltonline.org/article/S1053-2498(18)30296-1/abstract

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Lemaire, F., Bietiger, W., Peronet, C., Langlois, A., Mura, C., Bouzakri, K., Sigrist, S., Polard, V., Zal, F., Pinget, M., and Maillard, E. Effect of HEMO2life®, a marine oxygen carrier, for pancreas preservation during cold ischemia. Poster presented during 8th international EPITA Symposium,  Innsbruck, Austria. 2018

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Glorion, M., Polard, V., Favereau, F., Hauet, T., Zal, F., Fadel, E., Sage, E. Prevention of ischemia-reperfusion lung injury during static cold preservation by supplementation of standard preservation solution with HEMO2life® in pig lung transplantation model.  Artificial Cells, Nanomedicine, and Biotechnology, 46(8):1773-1780. 2018
https://www.ncbi.nlm.nih.gov/pubmed/29069926

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Polard, V., Alix, P. Evaluation of a specific oxygen carrier (M101®) added to pig liver cold storage solutions to improve post-transplant graft function. Presented at the XVI ISBS, held November 13-15, 2017 in Montréal, Canada. 2017

heart

Teh, E. S., Zal, F., Polard, V., Menasché, P., Chambers, D.J. HEMO2life® as a protective additive to Celsior solution for static storage of donor hearts prior to transplantation.  Artificial Cells, Nanomedicine, and Biotechnology, 45(4):717-722. 2017
https://www.ncbi.nlm.nih.gov/pubmed/28079401

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